Our study aimed to investigate the relationship between CAD and AF recurrence in patients who underwent RFCA.įor all enrolled patients, oral anticoagulant drugs (non-vitamin K antagonist oral anticoagulants, NOACs) were administered to the patients, and transoesophageal echocardiography was performed to rule out the possibility of an actual thrombus before the procedure. Few studies have investigated the association between revascularization for CAD and recurrence of AF after RFCA. In addition to RFCA therapy, PCI is required for AF and CAD patients with severe coronary artery stenosis.
Therefore, the success rate of RFCA is not very high. The success rate of atrial fibrillation after a single ablation procedure from different studies varies from 50 to 70% ( 13– 16).
However, the reported success rates of radiofrequency ablation in the treatment of AF are inconsistent. A previous meta-analysis proved that RFCA for AF had a higher efficacy rate than antiarrhythmic drug (AAD) therapy while having a lower rate of complications ( 12). Radiofrequency catheter ablation (RFCA) is an important treatment strategy for patients with symptomatic drug-refractory AF ( 11).
Because the risks for both diseases overlap, CAD is likely to coexist with AF, and patients often undergo percutaneous coronary intervention (PCI) as treatment ( 10). Multiple clinical risk factors, including hypertension, diabetes mellitus, increasing age, obesity, and sleep apnea, are shared by both diseases ( 9). Studies have revealed that the prevalence of CAD in patients with AF ranges from 17 to 46.5% ( 4– 8). Coronary artery disease (CAD) is a common cardiovascular disease and a leading cause of mortality ( 3). Patients with AF have a significantly higher risk of stroke and mortality ( 2). Additionally, For patients with CAD, coronary revascularization is related to a lower recurrence rate of AF after RFCA.Ītrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia, and its incidence increases significantly with age ( 1). The multivariate regression analysis showed that the other predictors of AF recurrence for obstructive CAD were multivessel stenosis (HR: 1.92 95% CI: 1.04–3.54 P = 0.036) and left atrial diameter (HR: 2.56 95% CI: 1.31–5.00 P = 0.006).Ĭonclusions: This study suggests that obstructive CAD is associated with a higher rate of AF recurrence. The recurrence rate of AF was significantly lower in patients who underwent PCI than in those who did not (HR: 0.45 95% CI: 0.25–0.80 P = 0.007). During the 24-month follow-up period, patients without obstructive CAD were significantly more likely to achieve freedom from AF than patients with obstructive CAD (hazard ratio : 1.72 95% confidence interval : 1.23–2.41 P = 0.001). Results: In total, 102, 95, and 212 patients were undergone coronary angiography and diagnosed as having obstructive CAD, Non-obstructive CAD, and Non-CAD, respectively. The endpoint was freedom from recurrence from AF after RFCA during the 24-month follow-up. Non-obstructive CAD was defined as coronary artery vessel stenosis of <75%. Obstructive CAD was defined as at least one coronary artery vessel stenosis of ≥75% and percutaneous coronary intervention (PCI) was recommended. Methods: Four hundred and nineteen patients who underwent performed coronary angiography at the same time as RFCA were enrolled in this study. This study aimed to explore the relationship between coronary revascularization and AF recurrence in patients who underwent radiofrequency catheter ablation (RFCA). Aim: The connection between revascularization for coronary artery disease (CAD) and the incidence of recurrent events of atrial fibrillation (AF) after ablation is unclear.